Three genes,
ced-2,
ced-5, and
ced-10 are required for both cell corpse engulfment and distal tip cell migration in C. elegans. Recently, a fourth gene,
ced-12, has been identified that is required for these two processes.
ced-12 encodes a novel, conserved adaptor molecule involved in the activation of Rho/Rac/CDC42-like GTPases.