[
Hum Exp Toxicol,
2001]
In general we agree with Dr. Rattan's thesis. Mutations that increase both life span and resistance to environmental stress have been documented in model systems as diverse as Caenorhabditis elegans, Drosophila melanogaster, and Mus musculus. The correlation between life extension (Age) and increased stress resistance is well established in C. elegans carrying single-gene