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Research Resources Reporter (DHHS),
1986]
A comprehensive collection of the nematode Caenorhabditis elegans, including strains useful in research and in teaching genetics, is maintained at the Caenorhabditis Genetics Center at the University of Missouri in Columbia, Missouri.
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Genome Biol,
2003]
The publication of the draft genome sequence of Caenorhabditis briggsae improves the annotation of the genome of its close relative Caenorhabditis elegans and will facilitate comparative genomics and the study of the evolutionary changes during development.
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Rivista Di Biologia Biology Forum,
1992]
Certain mutants of the nematode Caenorhabditis elegans exhibit an abnormal reiteration of specific cell divisions...
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Methods Mol Biol,
2006]
The genome of the nematode Caenorhabditis elegans was the first animal genome sequenced. Subsequent sequencing of the Caenorhabditis briggsae genome enabled a comparison of the genomes of two nematode species. In this chapter, we describe the methods that we used to compare the C. elegans genome to that of C. briggsae. We discuss how these methods could be developed to compare the C. elegans and C. briggsae genomes to those of Caenorhabditis remanei, C. n. sp. represented by strains PB2801 and CB5161, among others (1), and Caenorhabditis japonica, which are currently being sequenced.
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Curr Biol,
1994]
Two genes that control dauer formation in the soil nematode Caenorhabditis elegans have direct effects on senescence.
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Sci Robot,
2021]
Analysis of <i>Caenorhabditis elegans</i> natural movement and optogenetic control of its muscle cells enable controlled locomotion.
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WormBook,
2006]
Although several Caenorhabditis species are now studied in laboratories in great detail, the knowledge of the ecology of most Caenorhabditis species is scarce. In this chapter we present data on the habitat, animal associations, and geographical distribution of the eighteen described and five undescribed Caenorhabditis species currently known to science. The habitats of these species are very diverse, ranging from rotting cactus tissue to inflamed auditory canals of zebu cattle. Some species, including C. elegans , have only been isolated from anthropogenic habitats. Consequently, their natural habitat is unknown. All Caenorhabditis species are colonizers of nutrient- and bacteria-rich substrates and none of them is a true soil nematode. Dauer juveniles of many Caenorhabditis species were shown to be associated with terrestrial arthropods or gastropods. An association with invertebrates is also likely for the remaining species. The type of association is either phoresy (for transport to a new habitat) or necromeny (to secure the body of the associated animal as a future food source). There are also some records of Caenorhabditis species associated with vertebrates. The Caenorhabditis stem species was probably a colonizer of nutrient-rich substrates and was phoretic on arthropods. Some evolutionary trends within the taxon are discussed.
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[
Trends in Genetics,
1985]
Sexual phenotype in Caenorhabditis elegans is determined by a small number of control genes which are organized in a cascade of regulatory interactions.
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[
Ann N Y Acad Sci,
1959]
This paper is addressed primarily to the unsolved problems of culturing Caenorhabditis briggsae axenically. Included also are some comparative studies of related rhabditid nematodes.
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Expert Rev Anti Infect Ther,
2003]
The nematode worm, Caenorhabditis elegans, has been used to develop a facile model system of host-pathogen interactions to identify basic evolutionarily conserved pathways associated with microbial pathogenesis. The model involves the killing of Caenorhabditis elegans by a variety of human pathogens. Several virulence-related genes in a variety of pathogens previously shown to be involved in mammalian infection have also been shown to play a role in Caenorhabditis elegans killing. Screening of large numbers of microbial mutants for attenuation in a mammalian model would require thousands of mice, rats or rabbits. In contrast, the Caenorhabditis elegans model allows rapid identification of mutants in microbial genes associated with pathogenesis and then these phenotypes can be confirmed in a relevant mammalian model.