[
Trends Biochem Sci,
1994]
The Drosophila gene prospero (pros) encodes a sequence motif with similarity to homeodomains. This homeodomain motif is highly atypical, since it contains three extra residues between helix 2 and helix 3. Furthermore, some usually highly conserved residues are not conserved (for a comparison of atypical homeodomains see Ref. 4). ..