The localization of TRP-3/SPE-41 is initially confined to the membranous organelles in wild type spermatids. As the spermatids differentiate into spermatozoa, TRP-3/SPE-41 localizes to the cell surface. The localization of TRP-3/SPE-41 in
spe-38 mutant spermatids is indistinguishable from that of wild type spermatids. However, as the mutant spermatids differentiate into spermatozoa, TRP-3/SPE-41 fails to reach the cell surface.