"Although
lin-35/Rb mRNA levels were not significantly different, protein levels of this gene were reduced to about 20% in
mir-35- 41
(gk262) relative to wild type worm embryos (Figure 4A and 4B), suggesting that
mir-35-41 positively regulates the accumulation of LIN-35 protein. In contrast,
mir-35 miRNA levels were unaltered in
lin-35(
n745) mutant embryos (Figure 4C)."