"We therefore tested paraquat-induced expression of hsp-6
::gfp in loss-of-function mutants of skn-1
) and hif-1
). We found that none of the mutants prevented the induction of hsp-6
upon 0.5 mM paraquat exposure (Figure 5). This suggests that the response to paraquat triggers a pathway that does not require the transcription factors SKN-1, DAF-16 and HIF-1, and probably also not the pathways in which these factors are effectors namely the cytosolic stress response, insulin signaling, and the heat shock response."