DAF-16A::GFP was nuclear in many
akt-1(null) animals cultured on E. coli containing a control RNAi construct. Exposure of animals of the same genotype to
dpy-21 RNAi promoted the nuclear export and cytoplasmic retention of DAF-16A::GFP. Therefore, DPY-21 promotes the nuclear localization of DAF-16A::GFP.