"Elevated ROS levels appear essential for both the UPRmt activation and lifespan elongation in the
nduf-7(
et19) mutant because these phenotypes are abrogated by NAC, a hydrophilic antioxidant against all types of ROS (Aruoma et al. 1989; Benrahmoune et al. 2000; Yang and Hekimi 2010a) (Figure 6C, Figure 7)."