"C. elegans Src homology 3 (SH3) domain interactome was mapped using stringent yeast two hybrid, resulting in a total of 1070 interactions among 79 out of 84 worm SH3 domains and 475 proteins."
"C. elegans Src homology 3 (SH3) domain interactome was mapped using stringent yeast two hybrid, resulting in a total of 1070 interactions among 79 out of 84 worm SH3 domains and 475 proteins."
Query-target gene pairs were tested for interaction by feeding target gene RNAi to worms with a mutation in the query gene. Each query-target pair and its two controls were tested in at least three rounds.|Target genes were classified as either belonging to LGIII (L) or to signalling pathways (S) or to both (L,S): S