Mutation of the second position valine in the Walker B box of either protein (RFS-1 V135E or RIP-1 V128E) was sufficient to completely abolish the interaction in yeast two-hybrid, suggesting that the Walker B motifs mediate the RFS-1/RIP-1 interaction interface.
Mutation of the second position valine in the Walker B box of either protein (RFS-1 V135E or RIP-1 V128E) was sufficient to completely abolish the interaction in yeast two-hybrid, suggesting that the Walker B motifs mediate the RFS-1/RIP-1 interaction interface.
"We found that pcyt-1 RNAi was sufficient to activate lipogenic genes (as in (Walker et al., 2011)), innate immune genes (Figures S1E-S1J) and also induced PMK-1 phosphorylation (not shown)."
"We found that pcyt-1 RNAi was sufficient to activate lipogenic genes (as in (Walker et al., 2011)), innate immune genes (Figures S1E-S1J) and also induced PMK-1 phosphorylation (not shown)."
"We found that pcyt-1 RNAi was sufficient to activate lipogenic genes (as in (Walker et al., 2011)), innate immune genes (Figures S1E-S1J) and also induced PMK-1 phosphorylation (not shown)."
"We found that pcyt-1 RNAi was sufficient to activate lipogenic genes (as in (Walker et al., 2011)), innate immune genes (Figures S1E-S1J) and also induced PMK-1 phosphorylation (not shown)."
"We found that pcyt-1 RNAi was sufficient to activate lipogenic genes (as in (Walker et al., 2011)), innate immune genes (Figures S1E-S1J) and also induced PMK-1 phosphorylation (not shown)."
"We found that pcyt-1 RNAi was sufficient to activate lipogenic genes (as in (Walker et al., 2011)), innate immune genes (Figures S1E-S1J) and also induced PMK-1 phosphorylation (not shown)."