"C. elegans Src homology 3 (SH3) domain interactome was mapped using stringent yeast two hybrid, resulting in a total of 1070 interactions among 79 out of 84 worm SH3 domains and 475 proteins."
"The stable localization of WSP-1 was dependent on the presence of Arp2/3 complex, suggesting an interaction between the Arp2/3 complex and WSP-1 in vivo."
In arx-2(RNAi)-treated embryos, localization of WSP-1 at the periphery of cells was disrupted. In these embryos, WSP-1 was partially shifted to cell nuclei in blastomeres and migrating epithelial cells.