While 7% of embryos produced by
par-2(
it5ts) animals at the semi-restrictive temperature of 22C were viable, animals double mutant for
par-2 (
it5ts) and either
cyb-2.1(
tm2027) or
cyb-2.2(
tm1969) respectively produced 54% and 60% of viable progeny.
par-2 mutant embryos show cellular defects consistent with a loss of polarity such as central mitotic spindle positioning at the first embryonic division and loss of cell cycle asynchrony between AB and P1 divisions. These polarity defects were partially suppressed in double mutants for
par-2 and
cyb-2.1 at the semi-restrictive temperature of 22C.