The
daf-16(
m26);
daf-2(
e1370) double mutant has a similar sensitivity to cadmium as the
daf-16(
m26) individual mutant, more sensitive than wild type and much more sensitive than
daf-2(
e1370) alone. This result indicates that
daf-16(
m26) is epistatic to
daf-2(
e1370) with respect to cadmium sensitivity.