"C. elegans PDI/beta polypeptide forms an active prolyl 4-hydroxylase alpha2-beta2 tetramer with the human alpha subunit and an alpha-beta dimer with the C. elegans alpha subunit, whereas the C.elegans PDI isoform formed no prolyl 4-hydroxylase with either alpha subunit. Removal of the 32-residue C-terminal extension from the C. elegans alpha subunit totally eliminated alpha-beta dimer formation."
"C. elegans PDI/beta polypeptide forms an active prolyl 4-hydroxylase alpha2-beta2 tetramer with the human alpha subunit and an alpha-beta dimer with the C. elegans alpha subunit, whereas the C.elegans PDI isoform formed no prolyl 4-hydroxylase with either alpha subunit. Removal of the 32-residue C-terminal extension from the C. elegans alpha subunit totally eliminated alpha-beta dimer formation."