UNC-98 localizes to M-lines within wild-type C. elegans muscle cells. However,when paramyosin is absent from muscle cells as in the null mutant
unc-15(
e1214), UNC-98 no longer localizes to the M-lines and is randomly dispersed within the cells. The level of UNC-98 is depressed in the variation that might explain binding to UNC-98 and -96. absence of paramyosin (
unc-15(
e1214)).