The
hif-1(
ia4) mutation results in increased Pftn-1::GFP transgene expression and
egl-9(RNAi) results in a greater increase in Pftn-1::GFP transgene expression.
hif-1(
ia4);
egl-9(RNAi) animals have Pftn-1::GFP transgene expression indistinguishable from
hif-1(
ia4) mutants, suggesting that
hif-1(
ia4) is minimally epistatic to
egl-9(RNAi) with respect to Pftn-1::GFP transgene expression.