"RNAi using ds-RNA corresponding to the 3' UTR of exon 26 to specifically reduce the amount of medium (M) size class forms of UNC-52 was performed by feeding (see Materials and methods). When performed in a wild-type genetic background, no DTC defects were induced (data not shown); however, when performed on
unc-5(
e152) mutants, DTC defects were enhanced to the same level as doubles of class I alleles of
unc-52 with
unc-5(
e152) (Table 1)."