"We found that
met-2, a homolog of the mammalian H3K9 methyltransferase SETDB1 (Schultz et al., 2002; Bessler et al., 2010), was required for LIN-65 nuclear accumulation during induction of the UPRmt.
met-2(
ok2307) mutation strongly blocked the nuclear accumulation of
lin-65p::
lin-65::mCherry in the intestine on
cco-1 RNAi treatment (Figure 2A)."