Treatment with ionic liquids (ILs) for 2, 5 and 7 days slightly elevated
daf-16 expression. Nevertheless, with prolonged exposure for 9 and 11 days, ILs induced significant up-regulation of
daf-16 expression, corresponding with higher alive rate and longer lifespan. 1-octyl-2-methyl-3-methyl-imidazolium bromine ([OMMIM]Br), 1-decyl-2-methyl-3-methyl-imidazolium bromine ([DMMIM]Br),1-dodecyl-2-methyl-3-methyl-imidazolium bromine ([DoMMIM]Br)