Several regions in mec-3 promoter are protected by MEC-3 in the DNase I footprint. Alignment of MEC-3 binding sites (m) that overlap with UNC-86 binding sites reveals the consensus sequence ATAATNNAT. Alignment of MEC-3 binding sites (n) outside of the UNC-86 binding regions reveals the consensus sequence ANAAA.
Authors treated N2 worms with elt2 RNAi and measured OGT1 levels by RTqPCR. Authors found that elt2 RNAi decreased the mRNA levels of OGT1 in N2 worms.
RNAi targeting both F48E3.8 and C54G7.3 in N2 results in a modest delay in the development of F1 worms. This effect is synthetic as either RNAi alone does not show an effect in N2.
Authors treated N2 worms with elt2 RNAi and measured OGT1 levels by Western blots. Authors found that elt2 RNAi decreased the protein levels of OGT1 in N2 worms.
C25A8.5 is 3.835-fold over-expressed in eri-1(mg366) mutant compared to N2. C25A8.5 is 3.88-fold over-expressed in rrf-3(pk1426) mutant compared to N2.
C38C10.3 is 3.883-fold over-expressed in eri-1(mg366) mutant compared to N2. C38C10.3 is 4.52-fold over-expressed in rrf-3(pk1426) mutant compared to N2.
C54G4.3 is 3.386-fold over-expressed in eri-1(mg366) mutant compared to N2. C54G4.3 is 3.46-fold over-expressed in rrf-3(pk1426) mutant compared to N2.
F13G11.2 is 2.126-fold over-expressed in eri-1(mg366) mutant compared to N2. F13G11.2 is 2.2-fold over-expressed in rrf-3(pk1426) mutant compared to N2.