"
cmk-1 lin-45 double mutants exhibited almost normal calcium responses, showing that a loss-of-function mutation in
lin-45 suppressed the
cmk-1 abnormality (Figures 3B and 3D)... The expression of a
lin-45 cDNA, specifically in the AFD of
cmk-1 lin-45 double mutants, resulted in a phenotype similar to that of a
cmk-1 single mutant, suggesting that LIN-45 Raf acts cell-autonomously in AFD (Figure 3D)."