Under growth-promoting conditions, INS-18::Venus was weakly detected in head neurons, and it accumulated in the coelomocytes of wild-type animals at the adult stage. By contrast, the accumulation of Venus fluorescence was observed in head neurons in the
gon-1(
tm3146) mutant background, whereas INS-18:: Venus fluorescence intensity was decreased in the coelomocytes of
gon-1(
tm3146) mutants.