"To determine whether cdc-25.1
acts at G1/S or G2/M, we ectopically expressed mutant or wild-type cdc-25.1
under the control of the heat-shock promoter in adult worms carrying the rnr::GFP or cye-1
::GFP reporter constructs... Overexpression of mutant or wild-type cdc-25.1
caused adult intestinal cells to enter S phase, but did not cause any apparent lineage or morphological abnormalities in other tissues when animals were heat-shocked during larval or adult stages. Heat-shock alone had no effect on reporter expression (Fig. 6). "