"The ECM protein UNC-52/perlecan, at the top of the assembly dependence pathway, is organized normally in
pat-6(
st561) mutants, as can be seen by comparing wild-type (Figure 4A1) and
pat-6(
st561) (Figure 4A1') ~530 min embryos. In both the wild-type and
pat-6 embryos, UNC-52/perlecan is located in a continuous stripe within the basal lamina that subtends the body wall muscle cells. Integrin, which is just downstream from UNC-52/perlecan within the assembly dependence pathway, polarizes to the basal sarcolemma and enters into nascent attachment complexes in both wild-type and
pat-6 mutants. "