Deletion of individual TTLL enzymes does not impair viability or brood size, moreover microtubule morphology in the early embryo is unaffected (Chawla et al., 2016). The viability of the double mutants does not differ significantly from that of wild type in any case (Figure 1A, p>0.05; Student's t-test). The brood size of the double mutants does not differ significantly from wild type with two exceptions:
ttll-5 ttll-15 (p=0.04; Student's t-test) and
ttll-11;
ttll-15 (p=0.01 Student's t-test).