"To relate the effect of LWDH-EE on the molecular response in C. elegans, the transcript levels of three genes,
amy-1,
sod3 and
hsp16.2 were studied in transgenic C. elegans strain CL4176 after temperature upshift. Quantitative Real-Time PCR revealed differential expression of these genes after temperature upshift (Figure 4)... the
hsp16.2 transcript, which was higher at 10 h, further increased to more than six fold (p<0.05) with LWDH-EE treatment as compared to the control."