lin-35(lf) mutant abrogated the increased apoptosis phenotype induced by misc-1 RNAi. Authors suggest that these results suggest that misc-1 acts through the LIN-35/Rb-mediated physiological pathway of apoptosis.
"MCM-4::mCherry was not detected in other differentiated cells, such as muscle cells (Supplementary Fig. 2). lin-35 Rb mutants did not display deregulated expression of MCM-4::mCherry in any cell type (Table 1)."