A less substantial increase in germ cell apoptosis was observed in tiar-1(tm361);ced-1:gfp;ced-9(RNAi) animals, compared to ced-9(RNAi) alone, hence tiar-1(tm361) partially suppresses the increase in germ cell apoptosis caused by ced-9(RNAi).
"While interaction of RIC-3 with DEG-3 does not require assembly of DEG-3 with DES-2, it is enhanced by the presence of DES-2, suggesting that RIC-3 prefers DEG-3/DES-2 heteromers to DEG-3 monomers or homomers."