mml-1 : mxl-2
Mlx ortholog, named MXL-2 for Max-like 2, and a protein that has sequence features of both Myc and Mondo proteins, named MML-1 for Myc and Mondo-like 1. MML-1/MXL-2 complexes have a primary function in regulating migration of the ray 1 precursor cells in the male tail... MML-1/MXL-2 complexes control expression of ECM components in the non-migratory epidermis, which we propose contributes to the substratum required for migration of the neighboring ray 1 precursor cells... Pro-migratory Wnt/-catenin and semaphorin signaling pathways interact genetically with MML-1/MXL-2 to determine ray 1 position... MML-1/MXL-2 complexes and semaphorin signaling act in parallel pathways in adjacent cells and synergize to determine ray 1 position... Wnt/BAR-1 and semaphorin/plexin signaling cascades act in distinct, parallel pathways to modulate ray 1 precursor cell migration.