"Consistent with the reduced Pol II occupancy in
alg-3/4 males, the pre-mRNAs of positively regulated targets were also decreased in
alg-3/4 and
fer-15/rrf-3 males by 2- to 4-fold at 20C and by 4- to 8-fold at 25C. These findings suggest that both the Argonaute (ALG-3/4) and RdRP (FER-15/RRF-3) promote the transcription of positively regulated targets (Figure 4B)."