Glucosylceramide (GlcCer) levels reduction is enhanced by
cgt-2. GlcCer levels were further reduced when all three cgt genes were knocked down suggesting that
cgt-2 encodes a functional CGT protein. The level of GlcCer was 7.51.3 percent of wild type in this background compared to 243 percent of wild type when RNAi of
cgt-3 was done in the
cgt-1(
qa1809) background.