- non-replicative DNA transposition
Process by which a transposable element is excised from the donor site and integrated at the target site without replication of the element. Also referred to as cut-and-paste transposition.
- CUT catabolic process
The chemical reactions and pathways resulting in the breakdown of cryptic unstable transcripts (CUTs).
- CUT metabolic process
The chemical reactions and pathways involving cryptic unstable transcripts (CUTs), which are transcribed from intergenic regions. Many intergenic regions are heavily transcribed, but the transcripts are rarely detected due to rapid degradation by the nuclear exosome.
- nuclear polyadenylation-dependent CUT catabolic process
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a cryptic unstable transcript (CUT), initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target CUT.
- DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined, driven by ATP hydrolysis. The enzyme changes the linking number in multiples of 2.
- DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity
Binds to and increases the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
- DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity
Binds to and stops, prevents or reduces the activity of ATP-hydrolyzing DNA topoisomerase. ATP-hydrolyzing DNA topoisomerase catalyzes the DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
- DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity
Binds to and modulates the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.