Enables MATH domain binding activity; enzyme binding activity; and guanyl-nucleotide exchange factor activity. Involved in several processes, including myofibril assembly; pharyngeal gland morphogenesis; and regulation of striated muscle contraction. Located in M band. Expressed in alimentary muscle; gonad; tail; and vulval muscle. Human ortholog(s) of this gene implicated in centronuclear myopathy 5. Is an ortholog of human SPEG (striated muscle enriched protein kinase).
Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in neurons. Is an ortholog of human HOPX (HOP homeobox).
Predicted to enable glutamate decarboxylase activity and pyridoxal phosphate binding activity. Involved in GABAergic synaptic transmission. Located in axon; perikaryon; and synapse. Expressed in EF neuron and neurons. Used to study alcohol use disorder and epilepsy. Human ortholog(s) of this gene implicated in several diseases, including bipolar disorder; developmental and epileptic encephalopathy 89; and diabetes (multiple). Is an ortholog of human GAD1 (glutamate decarboxylase 1) and GAD2 (glutamate decarboxylase 2).
Enables several functions, including LIM domain binding activity; kinase binding activity; and protein-macromolecule adaptor activity. Involved in dephosphorylation and regulation of oviposition. Located in I band and M band. Expressed in body wall musculature; pharyngeal muscle cell; and vulval muscle. Is an ortholog of human CTDSP1 (CTD small phosphatase 1) and CTDSPL (CTD small phosphatase like).
Enables myosin binding activity. Involved in locomotion; regulation of cytoskeleton organization; and striated muscle myosin thick filament assembly. Located in M band and striated muscle myosin thick filament. Expressed in anal depressor muscle; body wall musculature; and pharyngeal muscle cell.
Involved in regulation of axon extension and regulation of synapse organization. Located in axon; neuronal cell body; and perinuclear region of cytoplasm. Expressed in CAN; HSN; ganglia; somatic nervous system; and touch receptor neurons. Is an ortholog of human SCOC (short coiled-coil protein).
Enables gap junction channel activity. Involved in several processes, including regulation of multicellular organismal process; reproductive behavior; and response to anesthetic. Located in gap junction and neuron projection membrane. Expressed in several structures, including OL socket cell; intestine; muscle cell; neurons; and pharyngeal gland cell.