Enables microtubule binding activity. Involved in chemotaxis; detection of stimulus involved in sensory perception; and intraciliary transport. Located in non-motile cilium. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 22; Joubert syndrome; and spermatogenic failure 58. Is an ortholog of human IFT74 (intraflagellar transport 74).
Is affected by several genes including daf-12; eat-2; and prg-1 based on tiling array and RNA-seq studies. Is affected by Microcystin-LR and sanguinarine based on microarray and RNA-seq studies.
Predicted to enable chitin binding activity. Involved in endoplasmic reticulum unfolded protein response. Predicted to be located in extracellular region.
Enables microtubule binding activity. Involved in chemotaxis; detection of stimulus involved in sensory perception; and intraciliary transport. Located in non-motile cilium. Expressed in amphid neurons; chemosensory neurons; and phasmid neurons. Human ortholog(s) of this gene implicated in short-rib thoracic dysplasia 19 with or without polydactyly. Is an ortholog of human IFT81 (intraflagellar transport 81).