Bma-unc-13

Brugia malayi

Predicted to enable diacylglycerol binding activity. Predicted to be involved in chemical synaptic transmission and intracellular signal transduction. Is an ortholog of C. elegans chrI_pilon.g1386 and unc-13. In C. elegans, unc-13 is involved in several processes, including regulation of pharyngeal pumping; regulation of reproductive process; and synaptic vesicle exocytosis.

Bm2384

Brugia malayi

Is affected by ivermectin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Vacuolar-sorting-associated 13 protein C-terminal; N-terminal region of Chorein or VPS13; Vacuolar sorting-associated protein 13, N-terminal; SHR-binding domain of vacuolar-sorting associated protein 13; Vacuolar protein sorting-associated protein 13, SHR-binding domain; Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13-like, N-terminal domain; Vacuolar protein sorting-associated protein 13, C-terminal; Vacuolar protein sorting-associated protein 13, second N-terminal domain; and Ricin B-like lectins. Is an ortholog of C. elegans C25H3.11 and chrII_pilon.g4582.

Bm5678

Brugia malayi

Is affected by ivermectin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Vacuolar-sorting-associated 13 protein C-terminal; Vacuolar sorting-associated protein 13, N-terminal; Repeating coiled region of VPS13; SHR-binding domain of vacuolar-sorting associated protein 13; N-terminal region of Chorein or VPS13; Vacuolar protein sorting-associated protein 13, SHR-binding domain; Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13-like, N-terminal domain; VPS13, repeated coiled region; Vacuolar protein sorting-associated protein 13, C-terminal; and Vacuolar protein sorting-associated protein 13, second N-terminal domain. Is an ortholog of C. elegans T08G11.1 and chrI_pilon.g1700.

Bma-abu-13

Brugia malayi

Is an ortholog of C. elegans abu-13 and chrIII_pilon.g8037.

Bm6565

Brugia malayi

Is an ortholog of C. elegans Y45F10B.13 and chrIV_pilon.g12328.

Bm5377

Brugia malayi

Predicted to enable DNA binding activity. Is an ortholog of C. elegans ceh-13; C10G8.2; and chrV_pilon.g14213. In C. elegans, ceh-13 is involved in cell-cell adhesion and embryo development.

Bma-hlh-13

Brugia malayi

Predicted to enable protein dimerization activity. Is an ortholog of C. elegans chrX_pilon.g18881 and hlh-13. In C. elegans, hlh-13 is involved in dauer exit; insulin receptor signaling pathway; and response to oxidative stress.

Bma-vha-13

Brugia malayi

Predicted to enable ATP binding activity. Predicted to be involved in ATP metabolic process. Is an ortholog of C. elegans chrV_pilon.g16506 and vha-13. In C. elegans, vha-13 is involved in lysosomal lumen acidification.

Bma-unc-50

Brugia malayi

Is predicted to encode a protein with the following domains: UNC-50 family and UNC-50. Is an ortholog of C. elegans chrIII_pilon.g8842 and unc-50. In C. elegans, unc-50 is involved in receptor localization to synapse and regulation of muscle contraction.

Bma-gei-13

Brugia malayi

Predicted to enable DNA binding activity. Is an ortholog of C. elegans chrIII_pilon.g8671 and gei-13.