seu-2

Caenorhabditis elegans

Acts upstream of or within dorsal/ventral axon guidance.

seu-3

Caenorhabditis elegans

Acts upstream of or within dorsal/ventral axon guidance.

unc-96

Caenorhabditis elegans

Enables myosin binding activity. Involved in locomotion; regulation of cytoskeleton organization; and striated muscle myosin thick filament assembly. Located in M band and striated muscle myosin thick filament. Expressed in anal depressor muscle; body wall musculature; and pharyngeal muscle cell.

C23G10.14

Caenorhabditis elegans

Is affected by several genes including rrf-3; unc-30; and unc-120 based on RNA-seq studies.

unc-69

Caenorhabditis elegans

Involved in regulation of axon extension and regulation of synapse organization. Located in axon; neuronal cell body; and perinuclear region of cytoplasm. Expressed in CAN; HSN; ganglia; somatic nervous system; and touch receptor neurons. Is an ortholog of human SCOC (short coiled-coil protein).

unc-7

Caenorhabditis elegans

Enables gap junction channel activity. Involved in several processes, including regulation of multicellular organismal process; reproductive behavior; and response to anesthetic. Located in gap junction and neuron projection membrane. Expressed in several structures, including OL socket cell; intestine; muscle cell; neurons; and pharyngeal gland cell.

unc-51

Caenorhabditis elegans

Enables protein kinase activity. Involved in several processes, including determination of adult lifespan; nematode male tail tip morphogenesis; and regulation of axon extension. Located in axon and neuronal cell body. Expressed in body wall musculature; motor neurons; pharyngeal muscle cell; and touch receptor neurons. Is an ortholog of human ULK1 (unc-51 like autophagy activating kinase 1) and ULK2 (unc-51 like autophagy activating kinase 2).

unc-46

Caenorhabditis elegans

Located in cytoplasmic vesicle and neuromuscular junction. Expressed in GLR and neurons.

unc-80

Caenorhabditis elegans

Enables cation channel activity. Involved in several processes, including cation homeostasis; positive regulation of locomotion; and response to anesthetic. Located in axon. Part of cation channel complex. Expressed in cholinergic neurons; excretory canal; hermaphrodite distal tip cell; non-striated muscle; and somatic nervous system. Is an ortholog of human UNC80 (unc-80 homolog, NALCN channel complex subunit).

unc-24

Caenorhabditis elegans

Predicted to be located in plasma membrane. Is an ortholog of human STOML1 (stomatin like 1).