Predicted to enable inositol monophosphate 1-phosphatase activity and metal ion binding activity. Involved in chemotaxis; protein localization to synapse; and thermotaxis. Located in cytoplasm. Expressed in several structures, including coelomocyte; gonad; intestine; neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 59; bipolar disorder; and schizophrenia. Is an ortholog of human IMPA1 (inositol monophosphatase 1) and IMPA2 (inositol monophosphatase 2).
Enables DNA-binding transcription factor activity and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including regulation of plasma membrane bounded cell projection assembly; thermosensory behavior; and transcription by RNA polymerase II. Located in nucleus. Expressed in head neurons and pharyngeal cell. Human ortholog(s) of this gene implicated in panhypopituitarism and syndromic microphthalmia 5. Is an ortholog of human OTX1 (orthodenticle homeobox 1).
Enables guanylate cyclase activity. Involved in microvillus organization and response to temperature stimulus. Located in microvillus membrane and neuron projection terminus. Expressed in AFDL and AFDR.
Expressed in body wall musculature; germ line; hypodermis; intestine; and pharynx. Is predicted to encode a protein with the following domains: Phosducin, N-terminal domain superfamily; Phosducin; Thioredoxin-like superfamily; and Phosducin, thioredoxin-like domain. Is an ortholog of human PDC (phosducin) and PDCL (phosducin like).
Involved in negative regulation of turning behavior involved in mating. Predicted to be located in extracellular region. Expressed in PVM; head; nerve ring; and tail.