Enables thioredoxin-disulfide reductase (NADP) activity. Involved in obsolete oxidation-reduction process. Located in mitochondrion. Expressed in intestine; muscle cell; nervous system; and vulva. Used to study chromosome 22q11.2 deletion syndrome, distal. Human ortholog(s) of this gene implicated in familial glucocorticoid deficiency. Is an ortholog of human TXNRD2 (thioredoxin reductase 2).
Predicted to enable thioredoxin-disulfide reductase (NADP) activity. Involved in ecdysis, collagen and cuticulin-based cuticle. Predicted to be located in cytosol and mitochondrion. Expressed in several structures, including hypodermis; interfacial epithelial cell; intestine; pharynx; and vulva. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; colorectal adenoma; and colorectal carcinoma. Is an ortholog of human TXNRD3 (thioredoxin reductase 3).
Predicted to enable translation elongation factor activity. Involved in selenocysteine incorporation. Is an ortholog of human EEFSEC (eukaryotic elongation factor, selenocysteine-tRNA specific).