Predicted to enable thioredoxin-disulfide reductase (NADP) activity. Involved in ecdysis, collagen and cuticulin-based cuticle. Predicted to be located in cytosol and mitochondrion. Expressed in several structures, including hypodermis; interfacial epithelial cell; intestine; pharynx; and vulva. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; colorectal adenoma; and colorectal carcinoma. Is an ortholog of human TXNRD3 (thioredoxin reductase 3).
Predicted to enable flavin adenine dinucleotide binding activity and thioredoxin-disulfide reductase (NADP) activity. Is an ortholog of C. elegans trxr-1. In C. elegans, trxr-1 is involved in ecdysis, collagen and cuticulin-based cuticle.
Predicted to enable flavin adenine dinucleotide binding activity and thioredoxin-disulfide reductase (NADP) activity. Is an ortholog of C. elegans trxr-1. In C. elegans, trxr-1 is involved in ecdysis, collagen and cuticulin-based cuticle.
Predicted to enable translation elongation factor activity. Involved in selenocysteine incorporation. Is an ortholog of human EEFSEC (eukaryotic elongation factor, selenocysteine-tRNA specific).