Predicted to enable sphinganine-1-phosphate aldolase activity. Involved in defense response to Gram-positive bacterium. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in nephrotic syndrome type 14. Is an ortholog of human SGPL1 (sphingosine-1-phosphate lyase 1).
Predicted to be located in endoplasmic reticulum membrane. Expressed in head; neurons; spermatheca; and vulva. Is an ortholog of human TMEM41B (transmembrane protein 41B).
Predicted to enable transferase activity. Involved in PERK-mediated unfolded protein response and innate immune response. Is an ortholog of human HPGDS (hematopoietic prostaglandin D synthase).
Predicted to enable metalloendopeptidase activity. Involved in PERK-mediated unfolded protein response. Predicted to be located in extracellular region.