sas-4

Caenorhabditis elegans

Involved in centriole replication and maintenance of protein location. Located in centriole. Expressed in gonad; intestinal cell; and sperm.

sas-6

Caenorhabditis elegans

Enables identical protein binding activity and protein domain specific binding activity. Involved in centriole replication; protein localization; and regulation of cell cycle. Located in centriole and cytoplasm.

sas-5

Caenorhabditis elegans

Involved in centriole replication. Located in centriole and cytoplasm.

sas-1

Caenorhabditis elegans

Located in centriole. Expressed in sperm. Used to study orofaciodigital syndrome.

hyls-1

Caenorhabditis elegans

Involved in cilium assembly and foraging behavior. Located in centriole and non-motile cilium. Expressed in amphid neurons; inner labial neurons; and outer labial neurons. Human ortholog(s) of this gene implicated in hydrolethalus syndrome 1. Is an ortholog of human HYLS1 (HYLS1 centriolar and ciliogenesis associated).

sas-2

Caenorhabditis elegans

zyg-1

Caenorhabditis elegans

Enables identical protein binding activity and protein serine/threonine kinase activity. Involved in several processes, including non-membrane-bounded organelle assembly; regulation of cell cycle; and regulation of protein localization. Located in centriole and centrosome.

sas-7

Caenorhabditis elegans

Enriched in several structures, including ABalaaaarl; ABalaaaarr; germ line; head mesodermal cell; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on microarray and RNA-seq studies. Is affected by antimycin based on RNA-seq studies.

linc-67

Caenorhabditis elegans

Is affected by ints-4; unc-30; and alh-4 based on RNA-seq studies.

dnc-4

Caenorhabditis elegans

Part of dynactin complex. Is an ortholog of human DCTN4 (dynactin subunit 4).