- rhi-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable Rho GDP-dissociation inhibitor activity. Predicted to be involved in Rho protein signal transduction. Located in cytosol and membrane. Human ortholog(s) of this gene implicated in nephrotic syndrome type 8. Is an ortholog of human ARHGDIA (Rho GDP dissociation inhibitor alpha); ARHGDIB (Rho GDP dissociation inhibitor beta); and ARHGDIG (Rho GDP dissociation inhibitor gamma).
- tag-325 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in signal transduction. Predicted to be located in cytoplasm. Is an ortholog of human ARHGAP12 (Rho GTPase activating protein 12); ARHGAP27 (Rho GTPase activating protein 27); and ARHGAP9 (Rho GTPase activating protein 9).
- rhgf-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of Rho protein signal transduction. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with midbrain and hindbrain malformations. Is an ortholog of human ARHGEF2 (Rho/Rac guanine nucleotide exchange factor 2).
- rga-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable GTPase activator activity. Predicted to be involved in Rho protein signal transduction; regulation of axonogenesis; and regulation of cell size. Predicted to be located in cytosol. Is an ortholog of human ARHGAP35 (Rho GTPase activating protein 35) and ARHGAP5 (Rho GTPase activating protein 5).
- F36F2.1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable actin binding activity. Predicted to be involved in positive regulation of Rho protein signal transduction and positive regulation of transcription by RNA polymerase II. Located in endoplasmic reticulum. Is an ortholog of human ABRA (actin binding Rho activating protein).
- rga-8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable GTPase activator activity. Predicted to be involved in regulation of Rac protein signal transduction and regulation of actin cytoskeleton organization. Is an ortholog of human ARHGAP17 (Rho GTPase activating protein 17); ARHGAP44 (Rho GTPase activating protein 44); and SH3BP1 (SH3 domain binding protein 1).
- ephx-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable guanyl-nucleotide exchange factor activity. Expressed in anchor cell; anterior distal tip cell; head; posterior distal tip cell; and uterine toroidal epithelial cell. Is an ortholog of human ARHGEF16 (Rho guanine nucleotide exchange factor 16) and ARHGEF26 (Rho guanine nucleotide exchange factor 26).