- clk-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable Hsp90 protein binding activity and telomeric DNA binding activity. Involved in several processes, including DNA damage checkpoint signaling; determination of adult lifespan; and response to radiation. Located in cytoplasm. Expressed in several structures, including distal tip cell; gonad; head ganglion; and preanal ganglion neurons. Is an ortholog of human TELO2 (telomere maintenance 2).
- gst-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable glutathione transferase activity. Involved in innate immune response. Expressed in intestine and nerve ring. Is an ortholog of human HPGDS (hematopoietic prostaglandin D synthase).
- rad-23 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable polyubiquitin modification-dependent protein binding activity; proteasome binding activity; and ubiquitin binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol and nucleoplasm. Expressed in dorsal nerve cord; head; neurons; ventral nerve cord; and vulva. Is an ortholog of human RAD23A (RAD23 homolog A, nucleotide excision repair protein).
- rad-8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable oxidoreductase activity. Involved in several processes, including defense response to other organism; positive regulation of growth rate; and response to superoxide. Located in mitochondrion. Expressed in several structures, including intestine; muscle cell; neurons; and pharynx. Human ortholog(s) of this gene implicated in optic atrophy 10. Is an ortholog of human RTN4IP1 (reticulon 4 interacting protein 1).
- brc-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables single-stranded DNA binding activity. Involved in several processes, including DNA metabolic process; egg-laying behavior; and embryo development. Located in condensed nuclear chromosome.
- msh-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable double-stranded DNA binding activity. Involved in chiasma assembly. Located in nucleus. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma; primary ovarian insufficiency 13; and spermatogenic failure. Is an ortholog of human MSH5 (mutS homolog 5).
- clec-149 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable carbohydrate binding activity. Predicted to be located in external side of plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including acquired immunodeficiency syndrome; bronchopulmonary dysplasia; and tuberculosis (multiple). Is an ortholog of human CD209 (CD209 molecule) and FCER2 (Fc epsilon receptor II).