ceh-17 [Browse genome (BioProject PRJNA13758)] [Legacy GBrowse]
Is an ortholog of human PHOX2A (paired like homeobox 2A) and PHOX2B (paired like homeobox 2B). Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific. Is involved in axon guidance; positive regulation of transcription by RNA polymerase II; and regulation of axon extension. Localizes to the nucleus. Is expressed in DA8; head muscle; head neurons; and somatic nervous system. Human ortholog(s) of this gene are implicated in congenital central hypoventilation syndrome and congenital fibrosis of the extraocular muscles.