Involved in clathrin-dependent endocytosis and necroptotic process. Located in neuromuscular junction. Expressed in several structures, including coelomocyte; head; hermaphrodite gonad; intestine; and muscle cell. Human ortholog(s) of this gene implicated in acute myeloid leukemia and high grade glioma. Is an ortholog of human SH3GL1 (SH3 domain containing GRB2 like 1, endophilin A2); SH3GL2 (SH3 domain containing GRB2 like 2, endophilin A1); and SH3GL3 (SH3 domain containing GRB2 like 3, endophilin A3).
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. Is an ortholog of human CFAP57 (cilia and flagella associated protein 57).
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in amphid neurons; intestine; neuroblasts; and somatic nervous system.
Expressed in gonad; oocyte; and sperm. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; MSP (Major sperm protein) domain; PapD-like superfamily; and Immunoglobulin-like fold.