Enables cysteine-type deubiquitinase activity and ionotropic glutamate receptor binding activity. Involved in anterior/posterior axis specification, embryo; positive regulation of gene expression; and positive regulation of locomotion involved in locomotory behavior. Located in endosome and neuronal cell body. Expressed in body wall musculature; intestine; nervous system; pharynx; and vulval muscle. Is an ortholog of human USP46 (ubiquitin specific peptidase 46).
Predicted to enable molecular adaptor activity and molybdopterin molybdotransferase activity. Involved in regulation of development, heterochronic. Located in cytoplasm and nucleus. Expressed in hypodermis; seam cell; and vulval precursor cell.
Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including detection of chemical stimulus; generation of neurons; and positive regulation of exit from mitosis. Located in nucleus. Expressed in several structures, including QL.aa; QL.pp; QR.aa; QR.pp; and neurons. Is an ortholog of human INSM2 (INSM transcriptional repressor 2).
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC46A2 (solute carrier family 46 member 2).
Predicted to enable glycine transmembrane transporter activity. Predicted to be involved in gamma-aminobutyric acid transport; glycine transport; and neurotransmitter loading into synaptic vesicle. Located in synaptic vesicle. Expressed in neurons. Used to study alcohol use disorder. Is an ortholog of human SLC32A1 (solute carrier family 32 member 1).
Predicted to be involved in mitochondrial fission. Predicted to be located in mitochondrial outer membrane. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 1E. Is an ortholog of human SLC25A46 (solute carrier family 25 member 46).
Predicted to enable several functions, including ATP binding activity; RNA binding activity; and RNA helicase activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Is an ortholog of human DDX46 (DEAD-box helicase 46).