Predicted to enable several functions, including 4 iron, 4 sulfur cluster binding activity; NADH dehydrogenase (ubiquinone) activity; and nucleotide binding activity. Involved in several processes, including dauer exit; determination of adult lifespan; and inductive cell migration. Located in mitochondrion. Used to study mitochondrial complex I deficiency. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 4. Is an ortholog of human NDUFV1 (NADH:ubiquinone oxidoreductase core subunit V1).
Is affected by nuo-6 based on microarray studies. Is affected by six chemicals including Rifampin; Sirolimus; and allantoin based on RNA-seq and microarray studies.
Is affected by tdp-1; nhr-25; and nuo-6 based on microarray studies. Is affected by Atrazine; fluoranthene; and Microcystin-LR based on microarray studies.
Is affected by several genes including daf-16; fbf-1; and nuo-6 based on RNA-seq and microarray studies. Is affected by Cry5B based on microarray studies.
Predicted to enable phosphoric diester hydrolase activity. Predicted to be located in extracellular space. Is an ortholog of human SMPDL3B (sphingomyelin phosphodiesterase acid like 3B).