Enables serotonin binding activity and serotonin-gated chloride channel activity. Involved in several processes, including behavioral response to starvation; locomotory exploration behavior; and positive regulation of fatty acid beta-oxidation by serotonin receptor signaling pathway. Located in neuronal cell body and plasma membrane. Expressed in body wall musculature and neurons. Used to study cocaine abuse.
Enables serotonin:sodium:chloride symporter activity. Involved in serotonin uptake. Predicted to be located in neuron projection. Expressed in several structures, including nerve ring. Used to study cocaine abuse. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; alexithymia; and attention deficit hyperactivity disorder. Is an ortholog of human SLC6A4 (solute carrier family 6 member 4).