Involved in several processes, including determination of adult lifespan; negative regulation of autophagy; and response to heat. Expressed in excretory canal; hypodermis; neurons; somatic nervous system; and vulval precursor cell.
Is affected by rsr-2; mir-34; and eat-2 based on tiling array and microarray studies. Is affected by tetrabromobisphenol A; allantoin; and Sirolimus based on microarray studies.